Pioneer Pitch Day

The Human Genome + the Human Exposome = Your Health

In the push towards personalized medicine, the human genome should only be considered part of the equation. Epigenetic markers, influenced by a range of environmental factors, are also crucial to understanding a person’s susceptibility to disease. Recently there’s been a call to map the human exposome—i.e., all environmental exposures starting from conception, including nutritional, chemical, psychosocial, etc. With this ...more »

Submitted by (@elise0)

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A Story of Health: Health and Environment.

Multiple environments. Food. Chemicals. Social. Economic. Built. Connect the dots. Connect through stories. Kid next door with asthma. The couple who can't conceive. Little guy with a learning problem. How? Make it fun. “Piano steps” at subway, people stepped up. Art, music, movement, helps learning. Send in the clowns. No more ‘eat your spinach’, Taste the cool crunch of an apple in autumn. No more ...more »

Submitted by (@karin0)

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The Prevention Project: Melding Science, Law and Social Engagement to End Chemical-Related Disease

The action-oriented Prevention Project will rid the world of chemical-related diseases. The problem: Toxic chemicals are pervasive—hundreds of chemicals are in our tissues and bodily fluids—and are linked to scores of public health issues, including cancer, cardiovascular disease, asthma, and obesity. Existing legal and business approaches are doomed to fail because they focus on risk management—keeping exposure down ...more »

Submitted by (@malloy)

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Curing Crashes: A New Medical Approach to Diagnosing and Treating Unsafe Young Drivers

Each year, crashes lead the causes of death to young adults (ages 16-24): 4-fold more deaths than from cancer; 38-fold more than from Flu. Yet, despite strong science on risk factors and prevention interventions, we lack young driver clinical care models. Crash prevention relies largely on “one-size-fits-all” driving laws rather than the IOM-recommended tiered risk approach: match prevention interventions with assessed ...more »

Submitted by (@flaura)

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Arsenic and Old Language: An Antidote for the Lethal Tobacco Ideology

An end to smoking, “the biggest killer in the world,” (WHO) is hastened via rigorous translation of science to public discourse. This proposal is anchored in neuroscience, social change analysis, and successful anti-smoking campaign strategies, all of which warrant dogged employment of internal event descriptors (poisonous, diseasing, lethal). While science correctly identified the problem 50 years ago, sadly we have ...more »

Submitted by (@plagergren)

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Systems Based Medicine Resource Group

Development and implementation of standardized clinical practice tools within medical systems is slow, costly, and often isolated to a single facility. On average, it takes 17 years for the average physician to adopt a Level 1 standard of care. It costs a minimum of $10,000 to develop and implement a Level 1 standard of care at a single hospital. The work to develop the clinical implementation tools is never shared with ...more »

Submitted by (@art.wallace)

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